ISSN 2146-8389
 

Brief Report 


Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study

Chidi N. Obasi, Karen J. Cruickshanks, David M. Nondahl, Barbara E. K. Klein, Ronald Klein, F. Javier Nieto, Anoop Shankar, Mary E. Fischer, Michael Y. Tsai, Rick Chappell.

Cited by (5)

Abstract
Individual biomarkers of inflammation, endothelial dysfunction and oxidative stress have been associated with cognitive impairment. This study explored whether a combination of biomarkers could prospectively identify those who developed cognitive decline. Biomarkers were obtained during the baseline examination of the Beaver Dam Eye Study (1988-90), and cognitive status was assessed during the 5-year follow-up examination of the Epidemiology of Hearing Loss Study (1998-2000). Cognitive impairment was defined as a score of < 24 points on the Mini-Mental State Examination or self- or proxy report of Alzheimer Disease or dementia. Among those with cognitive data, interleukin-6, isoprostanes, protein carbonyl, soluble intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 were available for 950 participants and 2,336 had high sensitivity C-reactive protein. Biomarkers of inflammation and endothelial dysfunction were not associated with cognitive impairment. There was a weak inverse association between higher levels of protein carbonyl content and cognitive impairment (OR, 0.8 per quartile of protein carbonyl content, P = 0.045 unadjusted for multiple comparisons). This was not significant on multiple testing and may have been a chance finding. We found that many markers of inflammation and endothelial dysfunction were not associated with cognitive impairment. An inverse association with carbonyl protein, a marker of oxidative stress needs further confirmation.

Key words: Biomarkers; Cognitive impairment; Inflammation; Oxidative stress


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Chidi N. Obasi
Articles by Karen J. Cruickshanks
Articles by David M. Nondahl
Articles by Barbara E. K. Klein
Articles by Ronald Klein
Articles by F. Javier Nieto
Articles by Anoop Shankar
Articles by Mary E. Fischer
Articles by Michael Y. Tsai
Articles by Rick Chappell
on Google
on Google Scholar
Article Statistics
 Viewed: 3937
Downloaded: 1172
Cited: 5

REFERENCES
1.Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 1998; 88:1337-42.

http://dx.doi.org/10.2105/AJPH.88.9.1337

[Pubmed]    [PMC Free Fulltext]   


2.Teunissen C, de Vente J, Steinbusch H, De Bruijn C. Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging 2002; 23:485-508.

http://dx.doi.org/10.1016/S0197-4580(01)00328-1

[
Pubmed]   


3.Roberts RO, Geda YE, Knopman DS, Boeve BF, Christianson TJ, Pankratz VS, Kullo IJ, Tangalos EG, Ivnik RJ, Petersen RC. Association of C-reactive protein with mild cognitive impairment. Alzheimers Dement 2009; 5:398-405.

http://dx.doi.org/10.1016/j.jalz.2009.01.025

[
Pubmed]    [PMC Free Fulltext]   


4.Yaffe K, Lindquist K, Penninx B, Simonsick EM, Pahor M, Kritchevsky S, Launer L, Kuller L, Rubin S, Harris T. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology 2003; 61:76-80.

http://dx.doi.org/10.1212/01.WNL.0000073620.42047.D7

[
Pubmed]   


5.Greilberger J, Koidl C, Greilberger M, Lamprecht M, Schroecksnadel K, Leblhuber F, Fuchs D, Oettl K. Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease. Free Radic Res 2008; 42:633-8.

http://dx.doi.org/10.1080/10715760802255764

[
Pubmed]   


6.Pratico D. Alzheimer's disease and oxygen radicals: new insights. Biochem Pharmacol 2002; 63:563-7.

http://dx.doi.org/10.1016/S0006-2952(01)00919-4

[
Pubmed]   


7.Song F, Poljak A, Smythe G, Sachdev P. Plasma biomarkers for mild cognitive impairment and Alzheimer's disease. Brain Res Rev 2009; 61:69-80.

http://dx.doi.org/10.1016/j.brainresrev.2009.05.003

[
Pubmed]   


8.Irizarry M, Yao Y, Hyman B, Growdon JH, PraticÚ D. Plasma F2A isoprostane levels in Alzheimer's and Parkinson's disease. Neurodegener Dis. 2007; 4:403-5.

http://dx.doi.org/10.1159/000107699

[
Pubmed]   


9.Zuliani G, Cavalieri M, Galvani M, Passaro A, Munari MR, Bosi C, Zurlo A, Fellin R. Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia. J Neurol Sci 2008; 272:164-70.

http://dx.doi.org/10.1016/j.jns.2008.05.020

[
Pubmed]   


10.Ewers M, Mielke M, Hampel H. Blood-based biomarkers of microvascular pathology in Alzheimer's disease. Exp Gerontol 2010; 45:75-9.

http://dx.doi.org/10.1016/j.exger.2009.09.005

[
Pubmed]    [PMC Free Fulltext]   


11.Richartz E, Stransky E, Batra A, Simon P, Lewczuk P, Buchkremer G, Bartels M, Schott K. Decline of immune responsiveness: a pathogenetic factor in Alzheimer's disease? J Psychiatr Res 2005; 39:535-43.

http://dx.doi.org/10.1016/j.jpsychires.2004.12.005

[
Pubmed]   


12.Hochstrasser T, Weiss E, Marksteiner J, Humpel C. Soluble cell adhesion molecules in monocytes of Alzheimer's disease and mild cognitive impairment. Exp Gerontol. 2010; 45:70-4.

http://dx.doi.org/10.1016/j.exger.2009.10.005

[
Pubmed]   


13.Albert MS, Dekosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH. The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging and Alzheimer's Association workgroup. Alzheimers Dement 2011; 7:270-9.

http://dx.doi.org/10.1016/j.jalz.2011.03.008

[
Pubmed]    [PMC Free Fulltext]   


14.Klein R, Klein B, Linton K, De Mets D. The Beaver Dam Eye Study: visual acuity. Ophthalmology 1991; 98:1310-5.

[
Pubmed]   


15.Cruickshanks K, Wiley T, Tweed T, Klein BE, Klein R, Mares-Perlman JA, Nondahl DM. Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin. The Epidemiology of Hearing Loss Study. Am J Epidemiol 1998; 148:879-86.

http://dx.doi.org/10.1093/oxfordjournals.aje.a009713

[
Pubmed]   


16.Cruickshanks K, Tweed T, Wiley T, Klein BE, Klein R, Chappell R, Nondahl DM, Dalton DS. The 5-year incidence and progression of hearing loss: the epidemiology of hearing loss study. Arch Otolaryngol Head Neck Surg 2003; 129:1041-6.

http://dx.doi.org/10.1001/archotol.129.10.1041

[
Pubmed]   


17.Schubert C, Carmichael L, Murphy C, Klein BE, Klein R, Cruickshanks KJ. Olfaction and the 5-year incidence of cognitive impairment in an epidemiological study of older adults. J Am Geriatr Soc 2008; 56:1517-21.

http://dx.doi.org/10.1111/j.1532-5415.2008.01826.x

[
Pubmed]    [PMC Free Fulltext]   


18.Carlsson CM, Nondahl DM, Klein BE, McBride PE, Sager MA, Schubert CR, Klein R, Cruickshanks KJ. Increased atherogenic lipoproteins are associated with cognitive impairment: effects of statins and subclinical atherosclerosis. Alzheimer Dis Assoc Disord 2009; 23:11-7.

http://dx.doi.org/10.1097/WAD.0b013e3181850188

[
Pubmed]    [PMC Free Fulltext]   


19.Smith C, Carney J, Starke-Reed P, Oliver C, Stadtman E, Floyd R, Markesbery W. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 1991; 88:10540-3.

http://dx.doi.org/10.1073/pnas.88.23.10540

[
Pubmed]    [PMC Free Fulltext]   


20.Stadtman ER. Protein oxidation in aging and age-related diseases. Ann N Y Acad Sci 2001; 928:22-38.

http://dx.doi.org/10.1111/j.1749-6632.2001.tb05632.x

[
Pubmed]   


21.Schmidt R, Schmidt H, Curb J, Masaki K, White LR, Launer LJ. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol 2002; 52:168-74.

http://dx.doi.org/10.1002/ana.10265

[
Pubmed]   


22.Ravaglia G, Forti P, Maioli F, Chiappelli M, Montesi F, Tumini E, Mariani E, Licastro F, Patterson C. Blood inflammatory markers and risk of dementia: The Conselice Study of Brain Aging. Neurobiol Aging 2007; 28:1810-20.

http://dx.doi.org/10.1016/j.neurobiolaging.2006.08.012

[
Pubmed]   


23.Tan Z, Beiser A, Vasan R, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology 2007; 68:1902-8.

http://dx.doi.org/10.1212/01.wnl.0000263217.36439.da

[
Pubmed]   


24.Jenny NS, French B, Arnold AM, Strotmeyer ES. Cushman M. Chaves PH, Ding J, Fried LP, Kritchevsky SB, Rifkin DE, Sarnak MJ, Newman AB. Long-term Assessment of Inflammation and Healthy Aging in Late Life: The Cardiovascular Health Study All Stars. J Gerontol A Biol Sci Med Sci 2012; 67:970-6.

http://dx.doi.org/10.1093/gerona/glr261

[
Pubmed]   


This Article Cited By the following articles

Circulating Cellular Adhesion Molecules and Cognitive Function: The Coronary Artery Risk Development in Young Adults Study
Front. Cardiovasc. Med. 2017; 4(): .

1
 
Endothelial Activation Is Associated With Cognitive Performance in Patients With Hypertension
American Journal of Hypertension 2016; 29(4): 464-469.

2
 
A Human-Based Integrated Framework forAlzheimer‚€™s Disease Research
Journal of Alzheimer 2015; 47(4): 857-868.

3
 
Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1receptors and eNOS in functional hyperemia in the mouse somatosensory cortex
American Journal of Physiology - Heart and Circulatory Physiology 2015; 309(11): H1837-H1845.

4
 
Role of plant-based diets in the prevention and regression of metabolic syndrome and neurodegenerative diseases
Trends in Food Science & Technology 2014; 40(1): 62-81.

5
 

How to Cite this Article
Pubmed Style

Obasi CN, Cruickshanks KJ, Nondahl DM, Klein BEK, Klein R, Nieto FJ, Shankar A, Fischer ME, Tsai MY, Chappell R. Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxid Antioxid Med Sci. 2012; 1(3): 169-173. doi:10.5455/oams.031212.br.004


Web Style

Obasi CN, Cruickshanks KJ, Nondahl DM, Klein BEK, Klein R, Nieto FJ, Shankar A, Fischer ME, Tsai MY, Chappell R. Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. http://www.ejmoams.com/?mno=27936 [Access: August 20, 2018]. doi:10.5455/oams.031212.br.004


AMA (American Medical Association) Style

Obasi CN, Cruickshanks KJ, Nondahl DM, Klein BEK, Klein R, Nieto FJ, Shankar A, Fischer ME, Tsai MY, Chappell R. Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxid Antioxid Med Sci. 2012; 1(3): 169-173. doi:10.5455/oams.031212.br.004



Vancouver/ICMJE Style

Obasi CN, Cruickshanks KJ, Nondahl DM, Klein BEK, Klein R, Nieto FJ, Shankar A, Fischer ME, Tsai MY, Chappell R. Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxid Antioxid Med Sci. (2012), [cited August 20, 2018]; 1(3): 169-173. doi:10.5455/oams.031212.br.004



Harvard Style

Obasi, C. N., Cruickshanks, K. J., Nondahl, D. M., Klein, B. E. K., Klein, R., Nieto, F. J., Shankar, A., Fischer, M. E., Tsai, M. Y. & Chappell, R. (2012) Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxid Antioxid Med Sci, 1 (3), 169-173. doi:10.5455/oams.031212.br.004



Turabian Style

Obasi, Chidi N., Karen J. Cruickshanks, David M. Nondahl, Barbara E. K. Klein, Ronald Klein, F. Javier Nieto, Anoop Shankar, Mary E. Fischer, Michael Y. Tsai, and Rick Chappell. 2012. Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxidants and Antioxidants in Medical Science, 1 (3), 169-173. doi:10.5455/oams.031212.br.004



Chicago Style

Obasi, Chidi N., Karen J. Cruickshanks, David M. Nondahl, Barbara E. K. Klein, Ronald Klein, F. Javier Nieto, Anoop Shankar, Mary E. Fischer, Michael Y. Tsai, and Rick Chappell. "Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study." Oxidants and Antioxidants in Medical Science 1 (2012), 169-173. doi:10.5455/oams.031212.br.004



MLA (The Modern Language Association) Style

Obasi, Chidi N., Karen J. Cruickshanks, David M. Nondahl, Barbara E. K. Klein, Ronald Klein, F. Javier Nieto, Anoop Shankar, Mary E. Fischer, Michael Y. Tsai, and Rick Chappell. "Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study." Oxidants and Antioxidants in Medical Science 1.3 (2012), 169-173. Print. doi:10.5455/oams.031212.br.004



APA (American Psychological Association) Style

Obasi, C. N., Cruickshanks, K. J., Nondahl, D. M., Klein, B. E. K., Klein, R., Nieto, F. J., Shankar, A., Fischer, M. E., Tsai, M. Y. & Chappell, R. (2012) Association of biomarkers for inflammation, endothelial dysfunction and oxidative stress with cognitive impairment: the Epidemiology of Hearing Loss Study. Oxidants and Antioxidants in Medical Science, 1 (3), 169-173. doi:10.5455/oams.031212.br.004





Most Viewed Articles
  • Low intensity radiofrequency radiation: a new oxidant for living cells
    Igor Yakymenko, Evgeniy Sidorik, Diane Henshel, Sergiy Kyrylenko
    Oxid Antioxid Med Sci. 2014; 3(1): 1-3
    » Abstract & References » doi: 10.5455/oams.240314.ed.002

  • Oxidants and antioxidants: friends or foes?
    Sukru Oter, Si Jin, Luca Cucullo, H.J. Damien Dorman
    Oxid Antioxid Med Sci. 2012; 1(1): 1-4
    » Abstract & References » doi: 10.5455/oams.080612.ed.001

  • Effects of free radicals and antioxidants on exercise performance
    Sikiru Lamina, Charles I. Ezema, Anele I. Theresa, Ezugwu U. Anthonia
    Oxid Antioxid Med Sci. 2013; 2(2): 83-91
    » Abstract & References » doi: 10.5455/oams.010413.rv.005

  • Effects of silymarin, N-acetylcysteine and selenium in the treatment of papulopustular acne
    Haidar Hamid Al-Anbari, Ahmed Salih Sahib, Ahmed R. Abu Raghif
    Oxid Antioxid Med Sci. 2012; 1(3): 201-207
    » Abstract & References » doi: 10.5455/oams.290912.or.019

  • Anticancer and free radical scavenging potency of Catharanthus roseus, Dendrophthoe petandra, Piper betle and Curcuma mangga extracts in breast cancer cell lines
    Wahyu Widowati, Tjandrawati Mozef, Chandra Risdian, Yellianty Yellianty
    Oxid Antioxid Med Sci. 2013; 2(2): 137-142
    » Abstract & References » doi: 10.5455/oams.100413.or.038

  • Antimicrobial and antioxidant properties of marine actinomycetes Streptomyces sp VITSTK7
    Mohankumar Thenmozhi, Krishnan Kannabiran
    Oxid Antioxid Med Sci. 2012; 1(1): 51-57
    » Abstract & References » doi: 10.5455/oams.270412.or.005

  • Is it oxidative or free radical stress and why does it matter?
    Boguslaw Lipinski
    Oxid Antioxid Med Sci. 2012; 1(1): 5-9
    » Abstract & References » doi: 10.5455/oams.130312.rv.001

  • Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro
    Ochuko L. Erukainure, Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, Muhammad Aliyu
    Oxid Antioxid Med Sci. 2012; 1(2): 127-132
    » Abstract & References » doi: 10.5455/oams.080712.or.009

  • Cytotoxic and proapoptotic activities of gallic acid to human oral cancer HSC-2 cells
    Alyssa G. Schuck, Jeffrey H. Weisburg, Hannah Esan, Esther F. Robin, Ayelet R. Bersson, Jordana R. Weitschner, Tova Lahasky, Harriet L. Zuckerbraun, Harvey Babich
    Oxid Antioxid Med Sci. 2013; 2(4): 265-274
    » Abstract & References » doi: 10.5455/oams.220713.or.051

  • Phytochemical and in vitro antioxidant properties of the methanolic extract of fruits of Blighia sapida, Vitellaria paradoxa and Vitex doniana
    Rabiat U. Hamzah, Evans C. Egwim, Adamu Y. Kabiru, Mary B. Muazu
    Oxid Antioxid Med Sci. 2013; 2(3): 217-223
    » Abstract & References » doi: 10.5455/oams.090513.or.043

  • Most Downloaded
  • Low intensity radiofrequency radiation: a new oxidant for living cells
    Igor Yakymenko, Evgeniy Sidorik, Diane Henshel, Sergiy Kyrylenko
    Oxid Antioxid Med Sci. 2014; 3(1): 1-3
    » Abstract & References » doi: 10.5455/oams.240314.ed.002

  • Oxidants and antioxidants: friends or foes?
    Sukru Oter, Si Jin, Luca Cucullo, H.J. Damien Dorman
    Oxid Antioxid Med Sci. 2012; 1(1): 1-4
    » Abstract & References » doi: 10.5455/oams.080612.ed.001

  • The antioxidant capacity and immunomodulatory activity of stingless bee honeys proceeding from Costa Rica
    Gabriel Zamora, Kees Beukelman, Bert van den Berg, Maria Laura Arias, Eduardo Umana, Ingrid Aguilar, Linda Quarles van Ufford, Edwin van den Worm, Natalia Fallas, Rebeca Solorzano
    Oxid Antioxid Med Sci. 2015; 4(1): 49-55
    » Abstract & References » doi: 10.5455/oams.180415.or.084

  • Is it oxidative or free radical stress and why does it matter?
    Boguslaw Lipinski
    Oxid Antioxid Med Sci. 2012; 1(1): 5-9
    » Abstract & References » doi: 10.5455/oams.130312.rv.001

  • Antimicrobial and antioxidant properties of marine actinomycetes Streptomyces sp VITSTK7
    Mohankumar Thenmozhi, Krishnan Kannabiran
    Oxid Antioxid Med Sci. 2012; 1(1): 51-57
    » Abstract & References » doi: 10.5455/oams.270412.or.005

  • Anticancer and free radical scavenging potency of Catharanthus roseus, Dendrophthoe petandra, Piper betle and Curcuma mangga extracts in breast cancer cell lines
    Wahyu Widowati, Tjandrawati Mozef, Chandra Risdian, Yellianty Yellianty
    Oxid Antioxid Med Sci. 2013; 2(2): 137-142
    » Abstract & References » doi: 10.5455/oams.100413.or.038

  • Effects of free radicals and antioxidants on exercise performance
    Sikiru Lamina, Charles I. Ezema, Anele I. Theresa, Ezugwu U. Anthonia
    Oxid Antioxid Med Sci. 2013; 2(2): 83-91
    » Abstract & References » doi: 10.5455/oams.010413.rv.005

  • Protective properties of complex of quercetin, selenium, catechins and curcumin against DNA damage
    Jana Kadrabova, Marica Krajcovicova-Kudlackova, Alexander Madaric, Martina Valachovicova, Csilla Mislanova, Maria Korenovska
    Oxid Antioxid Med Sci. 2012; 1(3): 179-184
    » Abstract & References » doi: 10.5455/oams.180912.or.018

  • Airway antioxidant capacity and pH in chronic obstructive pulmonary disease
    Wei Lee, Hsien Loo, Paul S. Thomas
    Oxid Antioxid Med Sci. 2012; 1(3): 153-160
    » Abstract & References » doi: 10.5455/oams.300812.or.016

  • Heparin or EDTA; anticoagulant of choice in free radical estimation?
    Kuldeep Mohanty, Swetasmita Mishra, Jhumur Pani, Tarannum Hasan, Abhishek Purohit, Subhadra Sharma, Rima Dada
    Oxid Antioxid Med Sci. 2012; 1(1): 21-24
    » Abstract & References » doi: 10.5455/oams.130512.br.001

  • Most Cited Articles
  • Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro
    Ochuko L. Erukainure, Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, Muhammad Aliyu
    Oxid Antioxid Med Sci. 2012; 1(2): 127-132
    » Abstract & References » doi: 10.5455/oams.080712.or.009
    Cited : 13 times [Click to see citing articles]

  • Anticancer and free radical scavenging potency of Catharanthus roseus, Dendrophthoe petandra, Piper betle and Curcuma mangga extracts in breast cancer cell lines
    Wahyu Widowati, Tjandrawati Mozef, Chandra Risdian, Yellianty Yellianty
    Oxid Antioxid Med Sci. 2013; 2(2): 137-142
    » Abstract & References » doi: 10.5455/oams.100413.or.038
    Cited : 11 times [Click to see citing articles]

  • Role of free radicals and antioxidants in gynecological cancers: current status and future prospects
    Lokanatha Valluru, Subramanyam Dasari, Rajendra Wudayagiri
    Oxid Antioxid Med Sci. 2014; 3(1): 15-26
    » Abstract & References » doi: 10.5455/oams.201113.rv.011
    Cited : 10 times [Click to see citing articles]

  • Silymarin and naringenin protects nicotine induced oxidative stress in young rats
    Anshu Jain, Nidhi Dwivedi, Rakesh Bhargava, Swaran J.S. Flora
    Oxid Antioxid Med Sci. 2012; 1(1): 41-49
    » Abstract & References » doi: 10.5455/oams.130412.or.004
    Cited : 9 times [Click to see citing articles]

  • Phytochemical and in vitro antioxidant properties of the methanolic extract of fruits of Blighia sapida, Vitellaria paradoxa and Vitex doniana
    Rabiat U. Hamzah, Evans C. Egwim, Adamu Y. Kabiru, Mary B. Muazu
    Oxid Antioxid Med Sci. 2013; 2(3): 217-223
    » Abstract & References » doi: 10.5455/oams.090513.or.043
    Cited : 9 times [Click to see citing articles]

  • Palm vitamin E reduces oxidative stress, and physical and morphological alterations of erythrocyte membranes in streptozotocin-induced diabetic rats
    Fatmah Ali Matough, Siti Balkis Budin, Zariyantey Abdul Hamid, Santhana Raj Louis, Nasar Alwahaibi, Jamaludin Mohamed
    Oxid Antioxid Med Sci. 2012; 1(1): 59-68
    » Abstract & References » doi: 10.5455/oams.300412.or.006
    Cited : 8 times [Click to see citing articles]

  • Peroxidative index as novel marker of hydrogen peroxide involvement in lipid peroxidation from coal dust exposure
    Nia Kania, Bambang Setiawan, Edi Widjajanto, Nurdiana Nurdiana, M. Aris Widodo, H.M.S. Chandra Kusuma
    Oxid Antioxid Med Sci. 2012; 1(3): 209-215
    » Abstract & References » doi: 10.5455/oams.031012.or.020
    Cited : 8 times [Click to see citing articles]

  • Cytotoxic and proapoptotic activities of gallic acid to human oral cancer HSC-2 cells
    Alyssa G. Schuck, Jeffrey H. Weisburg, Hannah Esan, Esther F. Robin, Ayelet R. Bersson, Jordana R. Weitschner, Tova Lahasky, Harriet L. Zuckerbraun, Harvey Babich
    Oxid Antioxid Med Sci. 2013; 2(4): 265-274
    » Abstract & References » doi: 10.5455/oams.220713.or.051
    Cited : 7 times [Click to see citing articles]

  • Heparin or EDTA; anticoagulant of choice in free radical estimation?
    Kuldeep Mohanty, Swetasmita Mishra, Jhumur Pani, Tarannum Hasan, Abhishek Purohit, Subhadra Sharma, Rima Dada
    Oxid Antioxid Med Sci. 2012; 1(1): 21-24
    » Abstract & References » doi: 10.5455/oams.130512.br.001
    Cited : 6 times [Click to see citing articles]

  • Antimicrobial and antioxidant properties of marine actinomycetes Streptomyces sp VITSTK7
    Mohankumar Thenmozhi, Krishnan Kannabiran
    Oxid Antioxid Med Sci. 2012; 1(1): 51-57
    » Abstract & References » doi: 10.5455/oams.270412.or.005
    Cited : 6 times [Click to see citing articles]