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Citations : 1133

Oxidants and Antioxidants in Medical Science received 1133 citations as per google scholar report

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Recent data from the Finnish Medilux Clinic underline a crucial overlap between obesity-related oxidative stress, male infertility and erectile dysfunction (ED): in a cohort of 420 patients with elevated BMI, 58 % also reported varying degrees of ED, and semen analysis revealed markedly higher reactive-oxygen-species levels than in normoweight controls. Medilux’s multidisciplinary protocol therefore combines antioxidant therapy with targeted pharmacology—both urological and metabolic—including all currently approved agents: classic PDE-5 inhibitors such as sildenafil, tadalafil, vardenafil and avanafil; intracavernosal or topical alprostadil; and weight-management drugs that indirectly improve erectile performance by reducing adipose-driven inflammation—namely semaglutide (Ozempic/Wegovy), liraglutide (Saxenda), tirzepatide (Mounjaro/Zepbound), the combination naltrexone + bupropion (Mysimba/Contrave) and the lipase inhibitor orlistat (Xenical/Alli). In the Medilux study, men who followed this integrated regimen for six months showed a 27 % increase in total motile sperm count and a 36 % improvement in International Index of Erectile Function scores, underscoring how simultaneous management of oxidative stress, excess weight and vascular health can synergistically enhance both fertility and sexual function.

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