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Chemical properties of <i>Monodora myristica</i> and its protective potentials against free radicals <i>in vitro</i>

Ochuko L. Erukainure, Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, Muhammad Aliyu.

Cited by (13)

Abstract
Distortion of the balance between the production of reactive oxygen species and the body’s antioxidant defenses against them produces oxidative stress, which intensifies tissue damage. Spices have been reported to possess antioxidant properties which protect against ROS. <i>Monodora myristica</i> is among the common spices in Nigeria with reported medicinal properties. Its proximate composition, phytochemical constituents and antioxidant activities were investigated. The proximate composition ranged from 3.06 to 52.42% with nitrogen free extract having the highest value and ash content, lowest. Phytochemical screening of the spice showed the presence of alkaloids, flavonoids, phenols, tannins and saponins. The 1,1-diphenyl-2 picrylhydrazyl (DPPH) scavenging activity ranged from 16.9 to 71.15 mg gallic acid equivalents (GAE)/g. While the reducing power compared to the standard, gallic acid ranging from 0.028 to 0.126 mg GAE/g. <i>Monodora myristica</i> exhibited high antioxidant activities <i>in vitro</i>, signifying the protective potential of the spice against free radicals. The phytochemicals, phenolic and flavonoids in particular may be responsible for these effective antioxidant properties.

Key words: DPPH; Flavonoid; Phenol; Proximate


 
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How to Cite this Article
Pubmed Style

Erukainure OL, Oke OV, Owolabi FO, Kayode FO, Umanhonlen EE, Aliyu M. Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxid Antioxid Med Sci. 2012; 1(2): 127-132. doi:10.5455/oams.080712.or.009


Web Style

Erukainure OL, Oke OV, Owolabi FO, Kayode FO, Umanhonlen EE, Aliyu M. Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. http://www.ejmoams.com/?mno=21076 [Access: August 18, 2018]. doi:10.5455/oams.080712.or.009


AMA (American Medical Association) Style

Erukainure OL, Oke OV, Owolabi FO, Kayode FO, Umanhonlen EE, Aliyu M. Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxid Antioxid Med Sci. 2012; 1(2): 127-132. doi:10.5455/oams.080712.or.009



Vancouver/ICMJE Style

Erukainure OL, Oke OV, Owolabi FO, Kayode FO, Umanhonlen EE, Aliyu M. Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxid Antioxid Med Sci. (2012), [cited August 18, 2018]; 1(2): 127-132. doi:10.5455/oams.080712.or.009



Harvard Style

Erukainure, O. L., Oke, O. V., Owolabi, F. O., Kayode, F. O., Umanhonlen, E. E. & Aliyu, M. (2012) Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxid Antioxid Med Sci, 1 (2), 127-132. doi:10.5455/oams.080712.or.009



Turabian Style

Erukainure, Ochuko L., Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, and Muhammad Aliyu. 2012. Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxidants and Antioxidants in Medical Science, 1 (2), 127-132. doi:10.5455/oams.080712.or.009



Chicago Style

Erukainure, Ochuko L., Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, and Muhammad Aliyu. "Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro." Oxidants and Antioxidants in Medical Science 1 (2012), 127-132. doi:10.5455/oams.080712.or.009



MLA (The Modern Language Association) Style

Erukainure, Ochuko L., Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, and Muhammad Aliyu. "Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro." Oxidants and Antioxidants in Medical Science 1.2 (2012), 127-132. Print. doi:10.5455/oams.080712.or.009



APA (American Psychological Association) Style

Erukainure, O. L., Oke, O. V., Owolabi, F. O., Kayode, F. O., Umanhonlen, E. E. & Aliyu, M. (2012) Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro. Oxidants and Antioxidants in Medical Science, 1 (2), 127-132. doi:10.5455/oams.080712.or.009





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