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Author Statement

Invited Review 


Phytoestrogens in gynecology - antioxidative role

Milan M. Terzic, Jelena R. Dotlic.

Abstract
It has been shown that higher levels of estrogens in females protect them against aging by up-regulating the expression of antioxidant longevity-related genes. Phytoestrogens are naturally occurring polycyclic phenols found in certain plants that have weak estrogenic effects due to the fact that they are structurally and functionally similar to 17ß-estradiol, and thus, bind to estradiol receptors. Therefore, isoflavones and other phenolic compounds decrease the increased level of markers of oxidative stress and boost DNA resistance to oxidative damage. Consequently, menopausal women who are receiving phytoestrogens have multiple benefits. Synergetic action of estrogenic and antioxidative mechanism of action exerts positive effects on cardiovascular, immunological and central nervous system. Moreover, they can have potential role in prevention and treatment of some cancers. Therefore, it is advised that menopausal women should get phytoestrogen supplementation.

Key words: Antioxidants; Menopause; Phytoestrogens


 
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PMid:21685820

How to Cite this Article
Pubmed Style

Terzic MM, Dotlic JR. Phytoestrogens in gynecology - antioxidative role. Oxid Antioxid Med Sci. 2013; 2(1): 1-4. doi:10.5455/oams.030313.ir.001

Web Style

Terzic MM, Dotlic JR. Phytoestrogens in gynecology - antioxidative role. http://www.ejmoams.com/?mno=32470 [Access: May 22, 2018]. doi:10.5455/oams.030313.ir.001

AMA (American Medical Association) Style

Terzic MM, Dotlic JR. Phytoestrogens in gynecology - antioxidative role. Oxid Antioxid Med Sci. 2013; 2(1): 1-4. doi:10.5455/oams.030313.ir.001


Vancouver/ICMJE Style

Terzic MM, Dotlic JR. Phytoestrogens in gynecology - antioxidative role. Oxid Antioxid Med Sci. (2013), [cited May 22, 2018]; 2(1): 1-4. doi:10.5455/oams.030313.ir.001


Harvard Style

Terzic, M. M. & Dotlic, J. R. (2013) Phytoestrogens in gynecology - antioxidative role. Oxid Antioxid Med Sci, 2 (1), 1-4. doi:10.5455/oams.030313.ir.001


Turabian Style

Terzic, Milan M., and Jelena R. Dotlic. 2013. Phytoestrogens in gynecology - antioxidative role. Oxidants and Antioxidants in Medical Science, 2 (1), 1-4. doi:10.5455/oams.030313.ir.001


Chicago Style

Terzic, Milan M., and Jelena R. Dotlic. "Phytoestrogens in gynecology - antioxidative role." Oxidants and Antioxidants in Medical Science 2 (2013), 1-4. doi:10.5455/oams.030313.ir.001


MLA (The Modern Language Association) Style

Terzic, Milan M., and Jelena R. Dotlic. "Phytoestrogens in gynecology - antioxidative role." Oxidants and Antioxidants in Medical Science 2.1 (2013), 1-4. Print. doi:10.5455/oams.030313.ir.001


APA (American Psychological Association) Style

Terzic, M. M. & Dotlic, J. R. (2013) Phytoestrogens in gynecology - antioxidative role. Oxidants and Antioxidants in Medical Science, 2 (1), 1-4. doi:10.5455/oams.030313.ir.001




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