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Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study

Shishir R. Shetty, Subhas G. Babu, Sucheta Kumari, Arvind Karikal, Pushparaja Shetty, Shruthi Hegde.

Cited by (2)

Abstract
In the South-East Asian countries oral cancer is one among the commonly occurring malignancies due to tobacco use and quid chewing habits. Early stage diagnosis of the disease is reported to have a better prognosis. Sialochemistry studies involving antioxidants have recently gained importance as biomarkers for oral cancer risk assessment. The aim of this study was to estimate the levels of superoxide dismutase in saliva of patients with oral cancer, oral leukoplakia and healthy controls. Three study groups comprising of 25 oral cancer patients, 25 oral leukoplakia patients and 25 healthy controls were involved in the study. Saliva sample collected from the patients were evaluated superoxide dismutase by nitroblue tetrazolium (NBT) chloride method. The data obtained were analyzed using the one way ANOVA test. There was a significant difference between the levels of salivary superoxide dismutase in between oral cancer, oral leukoplakia groups when compared to healthy controls. The levels of salivary superoxide dismutase were significantly lower in oral cancer when compared to oral leukoplakia. These results suggest that salivary superoxide dismutase level estimation could be used to determine the risk of oral cancer as a non-invasive modality.

Key words: Leukoplakia; Oral cancer; Saliva; Superoxide dismutase


 
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This Article Cited By the following articles

Evaluation of salivary and serum lipid peroxidation, and glutathione in oral leukoplakia and oral squamous cell carcinoma
Journal of Oral Science 2014; 56(2): 135-142.

1
 
Implications of tobacco smoking on the oral health of older adults
Geriatrics & Gerontology International 2014; 14(3): 526-540.

2
 

How to Cite this Article
Pubmed Style

Shetty SR, Babu SG, Kumari S, Karikal A, Shetty P, Hegde S. Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxid Antioxid Med Sci. 2013; 2(1): 69-71. doi:10.5455/oams.090113.br.005


Web Style

Shetty SR, Babu SG, Kumari S, Karikal A, Shetty P, Hegde S. Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. http://www.ejmoams.com/?mno=29856 [Access: May 22, 2018]. doi:10.5455/oams.090113.br.005


AMA (American Medical Association) Style

Shetty SR, Babu SG, Kumari S, Karikal A, Shetty P, Hegde S. Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxid Antioxid Med Sci. 2013; 2(1): 69-71. doi:10.5455/oams.090113.br.005



Vancouver/ICMJE Style

Shetty SR, Babu SG, Kumari S, Karikal A, Shetty P, Hegde S. Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxid Antioxid Med Sci. (2013), [cited May 22, 2018]; 2(1): 69-71. doi:10.5455/oams.090113.br.005



Harvard Style

Shetty, S. R., Babu, S. G., Kumari, S., Karikal, A., Shetty, P. & Hegde, S. (2013) Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxid Antioxid Med Sci, 2 (1), 69-71. doi:10.5455/oams.090113.br.005



Turabian Style

Shetty, Shishir R., Subhas G. Babu, Sucheta Kumari, Arvind Karikal, Pushparaja Shetty, and Shruthi Hegde. 2013. Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxidants and Antioxidants in Medical Science, 2 (1), 69-71. doi:10.5455/oams.090113.br.005



Chicago Style

Shetty, Shishir R., Subhas G. Babu, Sucheta Kumari, Arvind Karikal, Pushparaja Shetty, and Shruthi Hegde. "Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study." Oxidants and Antioxidants in Medical Science 2 (2013), 69-71. doi:10.5455/oams.090113.br.005



MLA (The Modern Language Association) Style

Shetty, Shishir R., Subhas G. Babu, Sucheta Kumari, Arvind Karikal, Pushparaja Shetty, and Shruthi Hegde. "Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study." Oxidants and Antioxidants in Medical Science 2.1 (2013), 69-71. Print. doi:10.5455/oams.090113.br.005



APA (American Psychological Association) Style

Shetty, S. R., Babu, S. G., Kumari, S., Karikal, A., Shetty, P. & Hegde, S. (2013) Salivary superoxide dismutase levels in oral leukoplakia and oral squamous cell carcinoma; a clinicopathological study. Oxidants and Antioxidants in Medical Science, 2 (1), 69-71. doi:10.5455/oams.090113.br.005





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