ISSN 2146-8389
 

Original Research (Original Article) 


Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II)

Jinxia Li, Kenming Yu, Jianping Bai, Huizhi Zhang, Jianbin Chao.

Cited by (1)

Abstract
Objective: Many flavonoids are natural chelators and flavonoid-metal complexes have shown to possess significant cytotoxic activity. Apigenin (4’,5,7-trihydroxyflavone) is one of the active flavonoids found naturally in a variety of fruits and vegetables. In this study, a complex of apigenin with magnesium (Mg)(II) was synthesized and its radical-scavenging and antioxidant capacity was determined.
Methods: The complex of apigenin with magnesium (Mg)(II) has been synthesized by reflux with stirring. It was was characterized by fourier transform infrared spectroscopy (FTIR) in potassium bromide (KBr). Apigenin is coordinated with Mg(II) through oxygen atoms of -OH and 4-C=O groups. Kinetic studies of scavenging DPPH• free radical with apigenin and Mg(II) complex were done at room temperature.
Results: The complex of apigenin with Mg(II) was more reactive than free apigenin in means of scavenging DPPH• free radical.
Conclusion: Apigenin complex with Mg(II) ion may be benefit to further development as promising potential metal-based drug.

Key words: Apigenin; DPPH• ; Magnesium; FTIR


 
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This Article Cited By the following articles

Hydroxyflavone metal complexes - molecular structure, antioxidant activity and biological effects
Chemico-Biological Interactions 2017; 273(): 245.

1
 

How to Cite this Article
Pubmed Style

Li J, Yu K, Bai J, Zhang H, Chao J. Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxid Antioxid Med Sci. 2014; 3(3): 231-235. doi:10.5455/oams.240714.or.070


Web Style

Li J, Yu K, Bai J, Zhang H, Chao J. Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). http://www.ejmoams.com/?mno=162342 [Access: August 20, 2018]. doi:10.5455/oams.240714.or.070


AMA (American Medical Association) Style

Li J, Yu K, Bai J, Zhang H, Chao J. Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxid Antioxid Med Sci. 2014; 3(3): 231-235. doi:10.5455/oams.240714.or.070



Vancouver/ICMJE Style

Li J, Yu K, Bai J, Zhang H, Chao J. Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxid Antioxid Med Sci. (2014), [cited August 20, 2018]; 3(3): 231-235. doi:10.5455/oams.240714.or.070



Harvard Style

Li, J., Yu, K., Bai, J., Zhang, H. & Chao, J. (2014) Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxid Antioxid Med Sci, 3 (3), 231-235. doi:10.5455/oams.240714.or.070



Turabian Style

Li, Jinxia, Kenming Yu, Jianping Bai, Huizhi Zhang, and Jianbin Chao. 2014. Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxidants and Antioxidants in Medical Science, 3 (3), 231-235. doi:10.5455/oams.240714.or.070



Chicago Style

Li, Jinxia, Kenming Yu, Jianping Bai, Huizhi Zhang, and Jianbin Chao. "Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II)." Oxidants and Antioxidants in Medical Science 3 (2014), 231-235. doi:10.5455/oams.240714.or.070



MLA (The Modern Language Association) Style

Li, Jinxia, Kenming Yu, Jianping Bai, Huizhi Zhang, and Jianbin Chao. "Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II)." Oxidants and Antioxidants in Medical Science 3.3 (2014), 231-235. Print. doi:10.5455/oams.240714.or.070



APA (American Psychological Association) Style

Li, J., Yu, K., Bai, J., Zhang, H. & Chao, J. (2014) Synthesis, characterization and free radical scavenging activity of apigenin with or without magnesium(II). Oxidants and Antioxidants in Medical Science, 3 (3), 231-235. doi:10.5455/oams.240714.or.070





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